Breast Secretory Carcinoma: Case Report and Brief Review of the Literature

Abstract

Secretory breast carcinoma (SBC) is a rare, low-grade breast carcinoma that is frequently difficult to diagnose due to its uncommon presentation and histological characteristics. We report a case of a 39-year-old female who presented with a palpable breast mass in her right breast. Two years earlier, mammographic studies were inconclusive for a localized right breast thickening but favored a benign process. The patient did not follow the recommendation to follow up until two years later when she observed a gradual mass enlargement. With tissue biopsy and appropriate investigations, she was diagnosed with SBC. The clinical presentation, diagnostic workup, and follow-up treatment strategy are summarized, and the excellent prognosis of localized SBC is stressed. Treatment modalities, including surgical interventions and adjuvant therapies, are reviewed for this tumor. The present case emphasizes the need for enhanced awareness among clinicians to facilitate an earlier diagnosis and management of secretory breast carcinoma for prompt treatment and a favorable patient outcome.

Keywords:

Secretory breast carcinoma, Immunohistochemistry, Molecular, Triple negative

Authors

  • Jaedyn Jones Ross University School of Medicine, Barbados
  • Angelina Shenouda California University of Science and Medicine, Colton, CA
  • Cary Pirtle Ross University School of Medicine, Barbados
  • Mariam Salis St George University School of Medicine, Grenada, West Indies
  • Isis Hernandez-Aguila Ross University School of Medicine, Barbados
  • Amruth Alluri American University of the Caribbean Medical School, USA
  • Anita Titus Ross University School of Medicine, Barbados
  • Jessica Borrero Ross University School of Medicine, Barbados
  • Shakira Rivera American University of the Caribbean Medical School, USA
  • Jessica Jahoda Research Writing & Publication (RWP), LLC, NY, USA
  • Mohamed Aziz Research Writing & Publication (RWP), LLC, NY, USA

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Published

12/25/2024

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Section

Articles